Prilosec

Prilosec (Brand name: omeprazole, sodium bicarbonate) is in the proton pump inhibitors (PPI) class of drugs. This medication works by impeding the production of stomach acid. FDA approved in 1989, Prilosec reduces the production of stomach acid by preventing the enzyme in the stomach wall from producing acid, which, in turn, allows the esophagus and stomach to heal.

Prilosec is used to treat Gastroesophageal Reflux Disease (GERD), ulcers and Zollinger-Ellison syndrome — all of which are caused by excess stomach acid. This medication is also used in critically ill patients for the prevention of upper GI bleeding. Prilosec is also prescribed to treat erosive esophagitis and heartburn. In combination with antibiotics, Prilosec is used to treat H. pylori infections.

Prilosec should be taken whole and before meals. The recommended dose of Prilosec for Gastroesophageal Reflux Disease, ulcers, H. pylori and erosive esophagitis is 20 to 40 mg on a daily basis. H. pylori infections are typically treated for 10 to 28 days, while ulcers take four to eight weeks of healing time. For heartburn, physicians generally prescribe 20 mg daily for a period of up to two weeks. The beginning dose for treating Zollinger-Ellison Syndrome is 60 mg daily; your Dallas physician will adjust your dose accordingly depending on your response.

Prilosec and other PPIs are well-tolerated. Nausea, vomiting, diarrhea, rash, headaches, and dizziness are the most common side effects. Water retention, abnormal heartbeat, nervousness, leg cramps, weakness, and muscle pain occur infrequently.

Because extended use (one year or longer) and high doses may increase the risk of wrist, hip and spine osteoporosis-related fractures, your Fort Worth doctor will prescribe the shortest duration and lowest dose needed to treat your condition.