Proton Pump Inhibitors Linked To Increased Risk Of Pneumonia

Proton pump inhibitors are a popular medication used to treat GERD, a disorder associated with frequent acid reflux. However, new research suggests that this medication class may increase a patient’s risk for developing community-acquired pneumonia.

It’s estimated hospital-acquired pneumonia results in 33,000 deaths per year. Researchers are concerned that these numbers may be affected by the common prescription of acid-suppressing medication to hospitalized patients—some of whom may not even need them. Researchs suggests that acid-blocking drugs given to reduce the risk of ulcers may increase the risk of developing pneumonia by as much as 30%.

How serious is this problem?

One study looked at 64,000 non-ventilated, non-ICU adult hospitalized patients and found that 52% were prescribed either proton pump inhibitors or H2 blockers in order to reduce acid production. These medications were prescribed within 48 hours of admission in 90% of cases. These patients were 30% more likely to develop pneumonia.

Each year, an estimated 20% of patients who develop hospital-acquired pneumonia will die due to the illness. Researchers suggest that doctors take a closer look at these preventative measures.